In February 2021, the members of the Committee on World Food Security (CFS) endorsed the first-ever Voluntary Guidelines on Food Systems and Nutrition (VGFSyN) aimed at supporting countries in their efforts to eradicate all forms of hunger and malnutrition, while strengthening the process towards sustainable food systems. This article investigates whether and how the VGFSyN address international trade, whose role in the functioning of food systems is clearly highlighted in current global policy initiatives. The analysis examines the relationship between trade policies and food security and nutrition. It highlights the most important positions on the matter of the members of the CFS during the preparation of the guidelines. We argue that the CFS missed the opportunity to include trade and its profound effect on nutrition in the supposedly systemic approach adopted in the guidelines. We believe that the VGFSyN would have been an ideal opportunity to emphasize the relationship between trade and food and nutrition security, and to call attention to the importance of trade in the transition towards sustainable food systems.